MolNFT v2 · #159021 · protein

Cryo-EM structure of vaccine-elicited antibody 0PV-c.01 in complex with HIV-1 Env BG505 DS-SOSIP and antibodies VRC03 and PGT122

6NF2: “Cryo-EM structure of vaccine-elicited antibody 0PV-c.01 in complex with HIV-1 Env BG505 DS-SOSIP and…”. Electron microscopy at 3.7, 3 ligands (NAG, MAN, BMA). MolNFT v2 #159021 on GenesisL1: 3D structure, binding sites and pockets…

PDB: 6NF2
Type: protein
Length: 3,867 residues
Chains: 24
Method: electron microscopy
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 3.7
Source: Homo sapiens; Human immunodeficiency virus 1
UniProt: Q2N0S6
Ligands: NAG, MAN, BMA

Structure

electron microscopy · resolution 3.7 · 8 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, G, Q	—	protein	453	—	Q2N0S6
B, I, R	—	protein	132	—	Q2N0S6
C, N, V	—	protein	128	—	—
D, M, U	—	protein	102	—	—
E, J, S	—	protein	132	—	—
F, K, T	—	protein	105	—	—
H, O, W	—	protein	125	—	—
L, P, X	—	protein	112	—	—

Ligands and binding sites

NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 105 copies · chains A, J, K, N, M, G, F, E, C, D, Q, T, S, V, U, B, I, R
MAN · alpha-D-mannopyranose · sugar · 48 copies · chains J, K, N, A, M, E, F, C, G, D, S, T, V, Q, U
BMA · beta-D-mannopyranose · sugar · 33 copies · chains J, A, N, E, G, C, S, Q, V

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q2N0S6
Elsewhere: RCSB PDB 6NF2 · PDBe 6NF2 · UniProt Q2N0S6

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