MolNFT v2 · #158856 · protein + DNA + RNA
Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA including RNA/DNA hybrid, and an incoming dTTP (LagS2)
6N9W: “Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and gp4 (helicase/primase) bound to DNA…”. Electron microscopy at 4.0, 3 ligands (TTP, MG, ZN). MolNFT v2 #158856 on GenesisL1: 3D structure, binding sites and…
- PDB
- 6N9W
- Type
- protein + DNA + RNA
- Length
- 2,440 residues
- Chains
- 9
- Method
- electron microscopy
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 4.0
- Source
- Enterobacteria phage T7; SYNTHETIC CONSTRUCT
- UniProt
- P03692, P00581
- Ligands
- TTP, MG, ZN
Structure
electron microscopy · resolution 4.0 · 9 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 496 | — | P03692 |
| B | — | protein | 474 | — | P03692 |
| C | — | protein | 276 | — | P03692 |
| D | — | protein | 261 | — | P03692 |
| E | — | protein | 241 | — | P03692 |
| F | — | protein | 17 | — | P03692 |
| H | — | protein | 645 | — | P00581 |
| P | — | rna | 6 | — | — |
| T | — | dna | 24 | — | — |
Ligands and binding sites
- TTP · Thymidine-5'-triphosphate · ligand · 5 copies · chains A, B, C, D, E, H, P, T
- MG · Magnesium ion · metal · 6 copies · chains B, C, D, E, H
- ZN · Zinc ion · metal · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6N9W · Structure of bacteriophage T7 lagging-strand DNA polymerase (D5A/E7A) and GP4… · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P03692
- Every structure of UniProt P00581
- Elsewhere: RCSB PDB 6N9W · PDBe 6N9W · UniProt P03692 · UniProt P00581
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