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MolNFT v2 · #158611 · protein + DNA

Ternary complex crystal structure of DNA polymerase Beta with 5-hydroxymethyl-dC (5-hmC) at the templating position

6N2T: “Ternary complex crystal structure of DNA polymerase Beta with 5-hydroxymethyl-dC (5-hmC) at the templating…”. X-ray diffraction at 2.6, 3 ligands (1GC, MG, NA). MolNFT v2 #158611 on GenesisL1: 3D structure, binding sites and pockets…

PDB
6N2T
Type
protein + DNA
Length
357 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v2 / PDB Bank
Contract
0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner
0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution
2.6
Source
Homo sapiens; SYNTHETIC CONSTRUCT
UniProt
P06746
Ligands
1GC, MG, NA

Structure

x-ray diffraction · resolution 2.6 · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein326—P06746
T—dna16——
P—dna10——
D—dna5——

Ligands and binding sites

  • 1GC · 2'-deoxy-5'-O-[(R)-hydroxy{[(s)-hydroxy(phosphonooxy) phosphoryl]methyl}phosphoryl]guanosine · ligand · chains A, T, P
  • MG · Magnesium ion · metal · 2 copies · chains A, P
  • NA · Sodium ion · metal · 2 copies · chains A, P, D

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6N2T · Ternary complex crystal structure of DNA polymerase beta with 5- hydroxymethyl-dc (5-hmc)… · the same entry in another collection · chain A against A, TM-score 1.00
  • P06746 · AlphaFold monomer V2.0 prediction for DNA polymerase beta (P06746) · a predicted model of the same protein · chain A against A, TM-score 0.95

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