MolNFT v2 · #158362 · protein + RNA
Cryo-EM structure of larger Csm-crRNA-target RNA ternary complex in type III-A CRISPR-Cas system
6MUS: “Cryo-EM structure of larger Csm-crRNA-target RNA ternary complex in type III-A CRISPR-Cas system”. Electron microscopy at 3.6, 1 ligand (ZN). MolNFT v2 #158362 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6MUS
- Type
- protein + RNA
- Length
- 2,587 residues
- Chains
- 10
- Method
- electron microscopy
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 3.6
- Source
- Thermococcus onnurineus; SYNTHETIC CONSTRUCT
- UniProt
- B6YWB8, B6YWB9, B6YWC0, B6YWC1, B6YWC2
- Ligands
- ZN
Structure
electron microscopy · resolution 3.6 · 10 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 772 | — | B6YWB8 |
| B | — | protein | 141 | — | B6YWB9 |
| C | — | protein | 277 | — | B6YWC0 |
| D | — | protein | 287 | — | B6YWC0 |
| E | — | protein | 279 | — | B6YWC1 |
| G | — | rna | 33 | — | — |
| H | — | rna | 25 | — | — |
| J | — | protein | 121 | — | B6YWB9 |
| K | — | protein | 275 | — | B6YWC0 |
| F | — | protein | 377 | — | B6YWC2 |
Ligands and binding sites
- ZN · Zinc ion · metal · 4 copies · chains A, C, D, K
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6MUS · Cryo-EM structure of larger csm-crrna-target RNA ternary complex in type III-a CRISPR-CAS… · the same entry in another collection · chain K against K, TM-score 1.00
- B6YWB8 · AlphaFold monomer V2.0 prediction for CRISPR system single-strand- specific… · a predicted model of the same protein · chain A against A, TM-score 0.98
- B6YWC1 · AlphaFold monomer V2.0 prediction for CRISPR system cms protein CSM4 (B6YWC1) · a predicted model of the same protein · chain E against A, TM-score 0.96
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B6YWB8
- Every structure of UniProt B6YWB9
- Every structure of UniProt B6YWC0
- Every structure of UniProt B6YWC1
- Every structure of UniProt B6YWC2
- Elsewhere: RCSB PDB 6MUS · PDBe 6MUS · UniProt B6YWB8 · UniProt B6YWB9 · UniProt B6YWC0 · UniProt B6YWC1 · UniProt B6YWC2
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