MolNFT v2 · #158006 · protein
X-ray crystal structure of darunavir-resistant-P51 HIV-1 protease in complex with GRL-121
6MK9: “X-ray crystal structure of darunavir-resistant-P51 HIV-1 protease in complex with GRL-121”. X-ray diffraction at 1.7, 1 ligand (7O7). MolNFT v2 #158006 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6MK9
- Type
- protein
- Length
- 198 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.7
- Source
- Human immunodeficiency virus 1
- UniProt
- O38893
- Ligands
- 7O7
Structure
x-ray diffraction · resolution 1.7 · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 99 | — | O38893 |
Ligands and binding sites
- 7O7 · (3S,3aR,5R,7aS,8S)-hexahydro-4H-3,5-methanofuro[2,3-b]pyran-8-yl {(2S,3R)-4-[{[2-(cyclopropylamino)-1,3-benzothiazol-6-yl]sulfonyl}(2-methylpropyl)amino]-3-hydroxy-1-phenylbutan-2-yl}carbamate · ligand · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6MK9 · X-ray crystal structure of darunavir-resistant-P51 HIV-1 protease in complex with grl-121 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O38893
- Elsewhere: RCSB PDB 6MK9 · PDBe 6MK9 · UniProt O38893
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