MolNFT v2 · #157396 · protein

A new V27M variant of beta 2 microglobulin induced amyloidosis in a patient with long-term hemodialysis

6M1B · Beta-2-microglobulin: “A new V27M variant of beta 2 microglobulin induced amyloidosis in a patient with long-term hemodialysis”. X-ray diffraction at 1.88, 3 ligands (MG, CA, PO4). MolNFT v2 #157396 on GenesisL1: 3D structure…

PDB: 6M1B
Type: protein
Length: 100 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.88
Source: Homo sapiens
Molecule: Beta-2-microglobulin
UniProt: P61769
Ligands: MG, CA, PO4

Structure

x-ray diffraction · resolution 1.88 · 1 distinct chain · 3% helix, 52% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Beta-2-microglobulin	protein	100	3% helix, 52% strand	P61769

Ligands and binding sites

MG · Magnesium ion · metal · chains A
CA · Calcium ion · metal · chains A
PO4 · Phosphate ion · ion · chains A
GOL · Glycerol · additive · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Modifications

Observed in the structure: 1 disulfide (disulfide).

Compared structures

6M1B · A new V27M variant of beta 2 microglobulin induced amyloidosis in a patient with… · the same entry in another collection · chain A against A, TM-score 1.00
P61769 · AlphaFold monomer V2.0 prediction for beta-2-microglobulin (P61769) · a predicted model of the same protein · chain A against A, TM-score 0.88

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P61769
Elsewhere: RCSB PDB 6M1B · PDBe 6M1B · UniProt P61769

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