MolNFT v2 · #157068 · protein
Crystal structure of the CBP bromodomain in complex with small molecule LC-CPin7
6LQX: “Crystal structure of the CBP bromodomain in complex with small molecule LC-CPin7”. X-ray diffraction at 2.46, 2 ligands (EOO, NA). MolNFT v2 #157068 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6LQX
- Type
- protein
- Length
- 455 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.46
- Source
- Homo sapiens
- UniProt
- I3L466
- Ligands
- EOO, NA
Structure
x-ray diffraction · resolution 2.46 · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B, A | — | protein | 115 | — | I3L466 |
| D | — | protein | 114 | — | I3L466 |
| C | — | protein | 111 | — | I3L466 |
Ligands and binding sites
- EOO · (1~{S},6~{R})-6-[(1-methoxycarbonyl-3,4-dihydro-2~{H}-quinolin-6-yl)carbamoyl]cyclohex-3-ene-1-carboxylic acid · ligand · chains B
- NA · Sodium ion · metal · 6 copies · chains B, A, D, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6LQX · Crystal structure of the cbp bromodomain in complex with small molecule lc-CPIN7 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt I3L466
- Elsewhere: RCSB PDB 6LQX · PDBe 6LQX · UniProt I3L466
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