MolNFT v2 · #156878 · protein
in meso full-length rat KMO in complex with a pyrazoyl benzoic acid inhibitor
6LKD: “in meso full-length rat KMO in complex with a pyrazoyl benzoic acid inhibitor”. X-ray diffraction at 3, 4 ligands (FAD, EGO, SO4). MolNFT v2 #156878 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6LKD
- Type
- protein
- Length
- 848 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 3
- Source
- Rattus norvegicus
- UniProt
- O88867
- Ligands
- FAD, EGO, SO4, CL
Structure
x-ray diffraction · resolution 3 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 427 | — | O88867 |
| B | — | protein | 421 | — | O88867 |
Ligands and binding sites
- FAD · Flavin-adenine dinucleotide · ligand · 2 copies · chains A, B
- EGO · 5-[5-(4-chloranyl-3-fluoranyl-phenyl)-4-methyl-pyrazol-1-yl]-2-phenylmethoxy-benzoic acid · ligand · 2 copies · chains A, B
- SO4 · Sulfate ion · ion · 2 copies · chains A, B
- CL · Chloride ion · ion · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6LKD · In meso full-length rat kmo in complex with a pyrazoyl benzoic acid inhibitor · the same entry in another collection · chain A against A, TM-score 1.00
- O88867 · AlphaFold monomer V2.0 prediction for kynurenine 3-monooxygenase (O88867) · a predicted model of the same protein · chain B against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O88867
- Elsewhere: RCSB PDB 6LKD · PDBe 6LKD · UniProt O88867
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