MolNFT v2 · #156417 · protein
Human Coagulation Factor XIIa (FXIIa) bound with the macrocyclic peptide F3 containing two (1S,2S)-2-ACHC residues
6L63: “Human Coagulation Factor XIIa (FXIIa) bound with the macrocyclic peptide F3 containing two (1S,2S)-2-ACHC…”. X-ray diffraction at 3, 2 ligands (ACE, NAG). MolNFT v2 #156417 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 6L63
- Type
- protein
- Length
- 493 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 3
- Source
- Homo sapiens; SYNTHETIC CONSTRUCT
- UniProt
- P00748
- Ligands
- ACE, NAG
Structure
x-ray diffraction · resolution 3 · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 228 | — | P00748 |
| B, D | — | protein | 18 | — | — |
| C | — | protein | 229 | — | P00748 |
Ligands and binding sites
- ACE · Acetyl group · ligand · 2 copies · chains A, B, C, D
- NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · 5 copies · chains A, C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6L63 · Human coagulation factor xiia (fxiia) bound with the macrocyclic peptide F3 containing… · the same entry in another collection · chain A against A, TM-score 1.00
- P00748 · AlphaFold monomer V2.0 prediction for coagulation factor XII (P00748) · a predicted model of the same protein · chain A against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P00748
- Elsewhere: RCSB PDB 6L63 · PDBe 6L63 · UniProt P00748
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