MolNFT v2 · #155610 · protein
Human MTHFD2 in complex with Compound 18
6KG2: “Human MTHFD2 in complex with Compound 18”. X-ray diffraction at 2.25, 3 ligands (D8C, NAD, PO4). MolNFT v2 #155610 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6KG2
- Type
- protein
- Length
- 583 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.25
- Source
- Homo sapiens
- UniProt
- P13995
- Ligands
- D8C, NAD, PO4
Structure
x-ray diffraction · resolution 2.25 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 293 | — | P13995 |
| B | — | protein | 290 | — | P13995 |
Ligands and binding sites
- D8C · N-[2-chloranyl-4-[[7-methyl-8-(4-methylpiperazin-1-yl)-5-oxidanylidene-2,4-dihydro-1H-chromeno[3,4-c]pyridin-3-yl]carbonyl]phenyl]methanesulfonamide · ligand · 2 copies · chains A, B
- NAD · Nicotinamide-adenine-dinucleotide · ligand · 2 copies · chains A, B
- PO4 · Phosphate ion · ion · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P13995
- Elsewhere: RCSB PDB 6KG2 · PDBe 6KG2 · UniProt P13995
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