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MolNFT v2 · #153661 · protein + DNA

Post-catalytic Complex of Human DNA Polymerase Mu with Templating Adenine and Mn-8oxodGMP

6IPD: “Post-catalytic Complex of Human DNA Polymerase Mu with Templating Adenine and Mn-8oxodGMP”. X-ray diffraction at 1.7, 3 ligands (OXD, MN, NA). MolNFT v2 #153661 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6IPD
Type
protein + DNA
Length
344 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v2 / PDB Bank
Contract
0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner
0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution
1.7
Source
Homo sapiens; SYNTHETIC CONSTRUCT
UniProt
Q9NP87
Ligands
OXD, MN, NA

Structure

x-ray diffraction · resolution 1.7 · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein326—Q9NP87
T—dna9——
P—dna5——
D—dna4——

Ligands and binding sites

  • OXD · Oxalic acid · ligand · chains A, P
  • MN · Manganese (II) ion · metal · 2 copies · chains A, P
  • NA · Sodium ion · metal · 2 copies · chains A, P
  • EDO · 1,2-ethanediol · additive · 3 copies · chains A, P
  • EPE · 4-(2-hydroxyethyl)-1-piperazine ethanesulfonic acid · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6IPD · Post-catalytic complex of human DNA polymerase mu with templating adenine and mn-8OXODGMP · the same entry in another collection · chain A against A, TM-score 1.00
  • Q9NP87 · AlphaFold monomer V2.0 prediction for DNA-directed DNA/RNA polymerase mu (Q9NP87) · a predicted model of the same protein · chain A against A, TM-score 0.99

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