MolNFT v2 · #153005 · protein

Thrombin in complex with fragment J02

6I51: “Thrombin in complex with fragment J02”. X-ray diffraction at 1.4, 4 ligands (F05, NAG, NA). MolNFT v2 #153005 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6I51
Type: protein
Length: 289 residues
Chains: 3
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.4
Source: Homo sapiens; SYNTHETIC CONSTRUCT
UniProt: P00734, P09945
Ligands: F05, NAG, NA, PO4

Structure

x-ray diffraction · resolution 1.4 · 3 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
L	—	protein	28	—	P00734
H	—	protein	250	—	P00734
I	—	protein	11	—	P09945

Ligands and binding sites

F05 · 1H-isoindol-3-amine · ligand · chains H
NAG · 2-acetamido-2-deoxy-beta-D-glucopyranose · sugar · chains H
NA · Sodium ion · metal · 2 copies · chains H
PO4 · Phosphate ion · ion · chains H
DMS · Dimethyl sulfoxide · additive · 2 copies · chains H

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6I51 · Thrombin in complex with fragment J02 · the same entry in another collection · chain H against H, TM-score 1.00
P09945 · AlphaFold monomer V2.0 prediction for hirudin variant-2 (P09945) · a predicted model of the same protein · chain I against A, TM-score 0.51

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00734
Every structure of UniProt P09945
Elsewhere: RCSB PDB 6I51 · PDBe 6I51 · UniProt P00734 · UniProt P09945

GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.