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MolNFT v2 · #152798 · protein + RNA

Crystal structure of DHX8 helicase bound to single stranded poly-adenine RNA

6HYU: “Crystal structure of DHX8 helicase bound to single stranded poly-adenine RNA”. X-ray diffraction at 3.22. MolNFT v2 #152798 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
6HYU
Type
protein + RNA
Length
1,207 residues
Chains
4
Method
x-ray diffraction
Collection
MolNFT v2 / PDB Bank
Contract
0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner
0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution
3.22
Source
Homo sapiens; SYNTHETIC CONSTRUCT
UniProt
Q14562

Structure

x-ray diffraction · resolution 3.22 · 4 distinct chains.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein613—Q14562
B—rna6——
C—protein585—Q14562
D—rna3——

Ligands and binding sites

  • EDO · 1,2-ethanediol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 6HYU · Crystal structure of DHX8 helicase bound to single stranded poly- adenine RNA · the same entry in another collection · chain A against A, TM-score 1.00
  • Q14562 · AlphaFold monomer V2.0 prediction for ATP-dependent RNA helicase DHX8 (Q14562) · a predicted model of the same protein · chain A against A, TM-score 0.95

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