MolNFT v2 · #152747 · protein
Human STK10 bound to a maleimide inhibitor
6HXF: “Human STK10 bound to a maleimide inhibitor”. X-ray diffraction at 2.09, 2 ligands (R70, CL). MolNFT v2 #152747 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6HXF
- Type
- protein
- Length
- 1,151 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.09
- Source
- Homo sapiens
- UniProt
- O94804
- Ligands
- R70, CL
Structure
x-ray diffraction · resolution 2.09 · 4 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | — | protein | 291 | — | O94804 |
| A | — | protein | 285 | — | O94804 |
| C | — | protein | 288 | — | O94804 |
| D | — | protein | 287 | — | O94804 |
Ligands and binding sites
- R70 · 3-(2-methoxyphenyl)-4-[[4-(phenylcarbonyl) phenyl]amino]pyrrole-2,5-dione · ligand · 4 copies · chains B, A, C, D
- CL · Chloride ion · ion · chains A
- EDO · 1,2-ethanediol · additive · 8 copies · chains B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6HXF · Human STK10 bound to a maleimide inhibitor · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O94804
- Elsewhere: RCSB PDB 6HXF · PDBe 6HXF · UniProt O94804
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