MolNFT v2 · #151753 · protein

A polyamorous repressor: deciphering the evolutionary strategy used by the phage-inducible chromosomal islands to spread in nature.

6H4B · ORF026: “A polyamorous repressor: deciphering the evolutionary strategy used by the phage-inducible chromosomal…”. X-ray diffraction at 2.902, 4 pockets (best druggability 0.60). MolNFT v2 #151753 on GenesisL1: 3D structure, binding…

PDB: 6H4B
Type: protein
Length: 219 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 2.902
Source: Staphylococcus aureus; Staphylococcus virus 69
Molecule: ORF026; Orf20
UniProt: Q4ZDP4, Q9F0J8
Pockets: 4 · best druggability 0.60

Structure

x-ray diffraction · resolution 2.902 · 2 distinct chains · 69% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	ORF026	protein	135	67% helix, 0% strand	Q4ZDP4
B	Orf20	protein	84	73% helix, 0% strand	Q9F0J8

Pockets

4 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	291	0.60	0.78	28	empty
2	61	0.46	0.83	11	empty
3	52	0.27	0.74	11	empty
4	55	0.27	0.73	13	empty

Interfaces

1 interface between chains.

A–B · 1158 Å² buried · 13 hydrogen bonds · protein-protein

Compared structures

6H4B · A polyamorous repressor: deciphering the evolutionary strategy used by the… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q4ZDP4
Every structure of UniProt Q9F0J8
Elsewhere: RCSB PDB 6H4B · PDBe 6H4B · UniProt Q4ZDP4 · UniProt Q9F0J8

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