MolNFT v2 · #151513 · protein

Carbonic Anhydrase CAIX mimic in complex with inhibitor JS13

6GXB: “Carbonic Anhydrase CAIX mimic in complex with inhibitor JS13”. X-ray diffraction at 1.35, 2 ligands (FF5, ZN). MolNFT v2 #151513 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6GXB
Type: protein
Length: 257 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.35
Source: Homo sapiens
UniProt: P00918
Ligands: FF5, ZN

Structure

x-ray diffraction · resolution 1.35 · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	257	—	P00918

Ligands and binding sites

FF5 · ~{N}-[4-[4-[(4-sulfamoylphenyl) carbamoylamino]phenoxy]butyl]ethanamide · ligand · chains A
ZN · Zinc ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6GXB · Carbonic anhydrase caix mimic in complex with inhibitor JS13 · the same entry in another collection · chain A against A, TM-score 1.00
P00918 · AlphaFold monomer V2.0 prediction for carbonic anhydrase 2 (P00918) · a predicted model of the same protein · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P00918
Elsewhere: RCSB PDB 6GXB · PDBe 6GXB · UniProt P00918

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