MolNFT v2 · #151244 · protein
Crystal structure of human GDP-D-mannose 4,6-dehydratase (E157Q) in complex with GDP-Man
6GPK: “Crystal structure of human GDP-D-mannose 4,6-dehydratase (E157Q) in complex with GDP-Man”. X-ray diffraction at 1.47, 2 ligands (NAP, GDD). MolNFT v2 #151244 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6GPK
- Type
- protein
- Length
- 1,386 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.47
- Source
- Homo sapiens
- UniProt
- O60547
- Ligands
- NAP, GDD
Structure
x-ray diffraction · resolution 1.47 · 3 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 350 | — | O60547 |
| C | — | protein | 342 | — | O60547 |
| D | — | protein | 344 | — | O60547 |
Ligands and binding sites
- NAP · Nadp nicotinamide-adenine-dinucleotide phosphate · ligand · 4 copies · chains A, B, C, D
- GDD · Guanosine-5'-diphosphate-alpha-D-mannose · ligand · 4 copies · chains A, B, C, D
- EDO · 1,2-ethanediol · additive · 28 copies · chains A, D, B, C
- GOL · Glycerol · additive · chains C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6GPK · Crystal structure of human GDP-D-mannose 4,6-dehydratase (E157Q) in complex with GDP-man · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O60547
- Elsewhere: RCSB PDB 6GPK · PDBe 6GPK · UniProt O60547
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