MolNFT v2 · #151026 · protein

Crystal structure of KRAS G12D (gppcp) in complex with bi 2852

6GJ8: “Crystal structure of KRAS G12D (gppcp) in complex with bi 2852”. X-ray diffraction at 1.65, 3 ligands (F0K, GCP, MG). MolNFT v2 #151026 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 6GJ8
Type: protein
Length: 169 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.65
Source: Homo sapiens
UniProt: P01116
Ligands: F0K, GCP, MG

Structure

x-ray diffraction · resolution 1.65 · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	169	—	P01116

Ligands and binding sites

F0K · (3~{S})-3-[2-[[[1-[(1-methylimidazol-4-yl)methyl]indol-6-yl]methylamino]methyl]-1~{H}-indol-3-yl]-5-oxidanyl-2,3-dihydroisoindol-1-one · ligand · chains A
GCP · Phosphomethylphosphonic acid guanylate ester · ligand · chains A
MG · Magnesium ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

6GJ8 · Crystal structure of KRAS G12D (gppcp) in complex with bi 2852 · the same entry in another collection · chain A against A, TM-score 1.00
P01116 · AlphaFold monomer V2.0 prediction for GTPase KRAS (P01116) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P01116
Elsewhere: RCSB PDB 6GJ8 · PDBe 6GJ8 · UniProt P01116

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