MolNFT v2 · #148050 · protein
O-GlcNAc Transferase in complex with covalent inhibitor
6E37: “O-GlcNAc Transferase in complex with covalent inhibitor”. X-ray diffraction at 2.531, 1 ligand (HQV). MolNFT v2 #148050 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6E37
- Type
- protein
- Length
- 704 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.531
- Source
- Homo sapiens; SYNTHETIC CONSTRUCT
- UniProt
- O15294
- Ligands
- HQV
Structure
x-ray diffraction · resolution 2.531 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 692 | — | O15294 |
| B | — | protein | 12 | — | — |
Ligands and binding sites
- HQV · (2S,3R,4R,5S,6R)-3-[(2E)-but-2-enoylamino]-4,5-dihydroxy-6-(hydroxymethyl)tetrahydro-2H-thiopyran-2-yl [(2R,3S,4R,5R)-5-(2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl]methyl dihydrogen diphosphate (non-preferred name) · ligand · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6E37 · O-glcnac transferase in complex with covalent inhibitor · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O15294
- Elsewhere: RCSB PDB 6E37 · PDBe 6E37 · UniProt O15294
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