MolNFT v2 · #143800 · protein
Crystal structure of BRD4 in complex with isoliquiritigenin and DMSO (Cocktail No. 3)
6AJV: “Crystal structure of BRD4 in complex with isoliquiritigenin and DMSO (Cocktail No. 3)”. X-ray diffraction at 1.45, 2 ligands (HCC, NA). MolNFT v2 #143800 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 6AJV
- Type
- protein
- Length
- 133 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.45
- Source
- Homo sapiens
- UniProt
- O60885
- Ligands
- HCC, NA
Structure
x-ray diffraction · resolution 1.45 · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 133 | — | O60885 |
Ligands and binding sites
- HCC · 2',4,4'-trihydroxychalcone · ligand · chains A
- NA · Sodium ion · metal · 3 copies · chains A
- DMS · Dimethyl sulfoxide · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 6AJV · Crystal structure of BRD4 in complex with isoliquiritigenin and dmso (cocktail no. 3) · the same entry in another collection · chain A against A, TM-score 1.00
- O60885 · AlphaFold monomer V2.0 prediction for bromodomain-containing protein 4 (O60885) · a predicted model of the same protein · chain A against A, TM-score 0.92
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O60885
- Elsewhere: RCSB PDB 6AJV · PDBe 6AJV · UniProt O60885
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