Ligand · HCC
HCC · 2',4,4'-trihydroxychalcone
HCC, 2',4,4'-trihydroxychalcone (C15 H12 O4, 256.3 g/mol), in the MolNFT structures on GenesisL1: bound in 7 records (4 PDB entries). Every binding site with its residues within 4.5 Å, the residues it binds most and the ligands found with…
- Component
- HCC
- Formula
- C15 H12 O4
- Class
- ligand
- Structures
- 7
- PDB entries
- 4
Binding sites
HCC in 7 structures; the first of them:
- 5YX4 · Isoliquiritigenin-complexed Chalcone isomerase (S189A) from the Antarctic vascular plant… · HCC A301 · binds ARG34, MET36, ILE38, PHE45, LEU100, GLN104, TYR105, LYS108
- 6AJV · Crystal structure of BRD4 in complex with isoliquiritigenin and DMSO (Cocktail No. 3) · HCC A202 · binds TRP81, PRO82, GLN85, PRO86, VAL87, ASP88, LYS91, LEU92 and 2 more
- 6AJX · Crystal structure of BRD4 in complex with isoliquiritigenin in the absence of DMSO · HCC A201 · binds TRP81, PRO82, PHE83, VAL87, LEU92, LEU94, TYR97, ASN135 and 4 more
- 9INV · Crystal structure of DAPK1 in complex with isoliquiritigenin · HCC A301 · binds LEU19, GLY20, SER21, GLY22, ALA25, VAL27, ALA40, LYS42 and 8 more
- 5YX4 · Isoliquiritigenin-complexed chalcone isomerase (S189A) from the antarctic vascular plant… · HCC A301 · binds ARG34, PHE45, LEU100, GLN104, TYR105, LYS108
- 6AJV · Crystal structure of BRD4 in complex with isoliquiritigenin and dmso (cocktail no. 3) · HCC A202 · binds TRP81, PRO82, GLN85, PRO86, VAL87, ASP88, LYS91, LEU92 and 2 more
- 6AJX · Crystal structure of BRD4 in complex with isoliquiritigenin in the absence of dmso · HCC A201 · binds TRP81, PRO82, PHE83, VAL87, LEU92, LEU94, TYR97, ASN135 and 3 more
Residues it binds most
LEU 7, ILE 6, PRO 4, VAL 5, ASP 3, LYS 5, TYR 4, ASN 2, GLN 4, PHE 4 (residue and the binding sites it lines).
Found with
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.