MolNFT v2 · #141421 · protein
The crystal structure of Lp-PLA2 in complex with a novel inhibitor
5YEA: “The crystal structure of Lp-PLA2 in complex with a novel inhibitor”. X-ray diffraction at 1.805, 2 ligands (8U9, SO4). MolNFT v2 #141421 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5YEA
- Type
- protein
- Length
- 743 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.805
- Source
- Homo sapiens
- UniProt
- Q13093
- Ligands
- 8U9, SO4
Structure
x-ray diffraction · resolution 1.805 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | — | protein | 372 | — | Q13093 |
| B | — | protein | 371 | — | Q13093 |
Ligands and binding sites
- 8U9 · 4-[[4-[4-chloranyl-3-(trifluoromethyl)phenoxy]-3-cyano-phenyl]sulfamoyl]benzoic acid · ligand · 2 copies · chains A, B
- SO4 · Sulfate ion · ion · 3 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5YEA · The crystal structure of lp-PLA2 in complex with a novel inhibitor · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q13093
- Elsewhere: RCSB PDB 5YEA · PDBe 5YEA · UniProt Q13093
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