MolNFT v2 · #141051 · protein
Phosphoglycerate mutase 1 (PGAM1) complexed with its inhibitor PGMI-004A
5Y2I: “Phosphoglycerate mutase 1 (PGAM1) complexed with its inhibitor PGMI-004A”. X-ray diffraction at 1.917, 2 ligands (8KX, CL). MolNFT v2 #141051 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5Y2I
- Type
- protein
- Length
- 467 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 1.917
- Source
- Homo sapiens
- UniProt
- P18669
- Ligands
- 8KX, CL
Structure
x-ray diffraction · resolution 1.917 · 2 distinct chains.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| B | — | protein | 233 | — | P18669 |
| C | — | protein | 234 | — | P18669 |
Ligands and binding sites
- 8KX · 3,4-bis(oxidanyl)-9,10-bis(oxidanylidene)-~{N}-[4-(trifluoromethyl)phenyl]anthracene-2-sulfonamide · ligand · chains B
- CL · Chloride ion · ion · chains B, C
- MES · 2-(N-morpholino)-ethanesulfonic acid · additive · chains C
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5Y2I · Phosphoglycerate mutase 1 (PGAM1) complexed with its inhibitor pgmi- 004A · the same entry in another collection · chain B against B, TM-score 1.00
- P18669 · AlphaFold monomer V2.0 prediction for phosphoglycerate mutase 1 (P18669) · a predicted model of the same protein · chain C against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P18669
- Elsewhere: RCSB PDB 5Y2I · PDBe 5Y2I · UniProt P18669
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