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MolNFT v2 · #136223 · protein

Identification of a New Zinc Binding Chemotype by Fragment Screening

5TY8: “Identification of a New Zinc Binding Chemotype by Fragment Screening”. X-ray diffraction at 1.45, 2 ligands (7Q1, ZN). MolNFT v2 #136223 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB
5TY8
Type
protein
Length
258 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v2 / PDB Bank
Contract
0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner
0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution
1.45
Source
Homo sapiens
UniProt
P00918
Ligands
7Q1, ZN

Structure

x-ray diffraction · resolution 1.45 · 1 distinct chain.

ChainMoleculeTypeResiduesSecondary structureUniProt
A—protein258—P00918

Ligands and binding sites

  • 7Q1 · (5R)-5-phenyl-1,3-oxazolidine-2,4-dione · ligand · chains A
  • ZN · Zinc ion · metal · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

  • 5TY8 · Identification of a new zinc binding chemotype by fragment screening · the same entry in another collection · chain A against A, TM-score 1.00
  • P00918 · AlphaFold monomer V2.0 prediction for carbonic anhydrase 2 (P00918) · a predicted model of the same protein · chain A against A, TM-score 1.00

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