MolNFT v2 · #122421 · protein

Crystal structure of a CDK inhibitor bound to CDK2

5IEY: “Crystal structure of a CDK inhibitor bound to CDK2”. X-ray diffraction at 1.66, 1 ligand (6AE). MolNFT v2 #122421 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5IEY
Type: protein
Length: 286 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.66
Source: Homo sapiens
UniProt: P24941
Ligands: 6AE

Structure

x-ray diffraction · resolution 1.66 · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	286	—	P24941

Ligands and binding sites

6AE · 4-[(4-{[(2R,3R)-3-hydroxybutan-2-yl]amino}pyrimidin-2-yl)amino]benzene-1-sulfonamide · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5IEY · Crystal structure of a cdk inhibitor bound to CDK2 · the same entry in another collection · chain A against A, TM-score 1.00
P24941 · AlphaFold monomer V2.0 prediction for cyclin-dependent kinase 2 (P24941) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P24941
Elsewhere: RCSB PDB 5IEY · PDBe 5IEY · UniProt P24941

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