MolNFT v2 · #122042 · protein
Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor
5I3O: “Crystal Structure of BMP-2-inducible kinase in complex with an Indazole inhibitor”. X-ray diffraction at 2.4, 2 ligands (IDV, SO4). MolNFT v2 #122042 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 5I3O
- Type
- protein
- Length
- 604 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.4
- Source
- Homo sapiens
- UniProt
- Q9NSY1
- Ligands
- IDV, SO4
Structure
x-ray diffraction · resolution 2.4 · 1 distinct chain.
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | — | protein | 302 | — | Q9NSY1 |
Ligands and binding sites
- IDV · N-(6-{3-[(dimethylsulfamoyl)amino]phenyl}-1H-indazol-3-yl)cyclopropanecarboxamide · ligand · 2 copies · chains A, B
- SO4 · Sulfate ion · ion · 2 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 5I3O · Crystal structure of bmp-2-inducible kinase in complex with an indazole inhibitor · the same entry in another collection · chain A against A, TM-score 1.00
- Q9NSY1 · AlphaFold monomer V2.0 prediction for bmp-2-inducible protein kinase (Q9NSY1) · a predicted model of the same protein · chain B against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q9NSY1
- Elsewhere: RCSB PDB 5I3O · PDBe 5I3O · UniProt Q9NSY1
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