MolNFT v2 · #118553 · protein

Crystal structure of the human BRPF1 bromodomain in complex with SEED19

5EWH: “Crystal structure of the human BRPF1 bromodomain in complex with SEED19”. X-ray diffraction at 1.63, 2 ligands (5SG, NO3). MolNFT v2 #118553 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 5EWH
Type: protein
Length: 113 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v2 / PDB Bank
Contract: 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
Owner: 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
Resolution: 1.63
Source: Homo sapiens
UniProt: P55201
Ligands: 5SG, NO3

Structure

x-ray diffraction · resolution 1.63 · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	113	—	P55201

Ligands and binding sites

5SG · isoquinolin-5-ol · ligand · chains A
NO3 · Nitrate ion · ion · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Compared structures

5EWH · Crystal structure of the human BRPF1 bromodomain in complex with SEED19 · the same entry in another collection · chain A against A, TM-score 1.00
P55201 · AlphaFold monomer V2.0 prediction for peregrin (P55201) · a predicted model of the same protein · chain A against A, TM-score 0.95

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P55201
Elsewhere: RCSB PDB 5EWH · PDBe 5EWH · UniProt P55201

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