MolNFT v2 · #103972 · protein
Phl p 4 I153V N158H variant, a glucose oxidase, 3.5 M NaBr soak
4PWC · Pollen allergen Phl p 4.0202: “Phl p 4 I153V N158H variant, a glucose oxidase, 3.5 M NaBr soak”. X-ray diffraction at 2.3, 3 ligands (FAD, NA, BR), 1 pocket (best druggability 0.82). MolNFT v2 #103972 on GenesisL1: 3D structure…
- PDB
- 4PWC
- Type
- protein
- Length
- 490 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v2 / PDB Bank
- Contract
- 0xd58B01f6C18086e5202cdC5D7Ad3E41790360102
- Owner
- 0xF4e1AA6f26B7DA48EeAD9B24a97927303eeA07b8
- Resolution
- 2.3
- Source
- Phleum pratense
- Molecule
- Pollen allergen Phl p 4.0202
- UniProt
- B2ZWE9
- Ligands
- FAD, NA, BR
- Pockets
- 1 · best druggability 0.82
Structure
x-ray diffraction · resolution 2.3 · 1 distinct chain · 36% helix, 21% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Pollen allergen Phl p 4.0202 | protein | 490 | 36% helix, 21% strand | B2ZWE9 |
Ligands and binding sites
- FAD · Flavin-adenine dinucleotide · ligand · chains A
- NA · Sodium ion · metal · 2 copies · chains A
- BR · Bromide ion · ion · 68 copies · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 632 | 0.82 | 0.87 | 81 | FAD, BR |
Modifications
Observed in the structure: 2 cofactor, 2 disulfide (flavinylation, disulfide).
Compared structures
- 4PWC · Phl P 4 I153V N158H variant, a glucose oxidase, 3.5 M nabr soak · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt B2ZWE9
- Elsewhere: RCSB PDB 4PWC · PDBe 4PWC · UniProt B2ZWE9
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