MolNFT v1 · #99846 · protein

Crystal structure of mycobacterium tuberculosis card

4MFR · RNA polymerase-binding transcription factor card: “Crystal structure of mycobacterium tuberculosis card”. X-ray diffraction, 2 ligands (IOD, SO4), 1 pocket (best druggability 0.58). MolNFT v1 #99846 on GenesisL1: 3D structure…

PDB: 4MFR
Type: protein
Length: 164 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: RNA polymerase-binding transcription factor card
UniProt: O53568
Ligands: IOD, SO4
Pockets: 1 · best druggability 0.58

Structure

x-ray diffraction · 1 distinct chain · 50% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	RNA polymerase-binding transcription factor card	protein	164	50% helix, 18% strand	O53568

Ligands and binding sites

IOD · Iodide ion · ion · 16 copies · chains A
SO4 · Sulfate ion · ion · 13 copies · chains A
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	304	0.58	0.77	36	IOD

Compared structures

4MFR · Crystal structure of Mycobacterium tuberculosis CarD · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt O53568
Elsewhere: RCSB PDB 4MFR · PDBe 4MFR · UniProt O53568

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