MolNFT v1 · #99185 · RNA

Structure of the thf riboswitch bound to 2,6-diaminopurine

4LVZ: “Structure of the thf riboswitch bound to 2,6-diaminopurine”. X-ray diffraction, 1 ligand (6AP), 3 pockets (best druggability 0.67). MolNFT v1 #99185 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4LVZ
Type: RNA
Length: 89 nucleotides
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Thf riboswitch
Ligands: 6AP
Pockets: 3 · best druggability 0.67

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Thf riboswitch	rna	89	—	—

Ligands and binding sites

6AP · 9H-purine-2,6-diamine · ligand · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	921	0.67	0.74	45	empty
2	194	0.48	0.76	20	empty
3	96	0.29	0.72	12	empty

Compared structures

4LVZ · Structure of the THF riboswitch bound to 2,6-diaminopurine · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 4LVZ · PDBe 4LVZ

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