MolNFT v1 · #99182 · RNA

Structure of the thf riboswitch bound to 7-deazaguanine

4LVW: “Structure of the thf riboswitch bound to 7-deazaguanine”. X-ray diffraction, 1 ligand (7DG), 3 pockets (best druggability 0.66). MolNFT v1 #99182 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4LVW
Type: RNA
Length: 89 nucleotides
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Thf riboswitch
Ligands: 7DG
Pockets: 3 · best druggability 0.66

Structure

x-ray diffraction · 1 distinct chain.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Thf riboswitch	rna	89	—	—

Ligands and binding sites

7DG · 7-deazaguanine · ligand · 2 copies · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	864	0.66	0.74	42	empty
2	201	0.47	0.76	21	empty
3	79	0.27	0.71	13	empty

Compared structures

4LVW · Structure of the THF riboswitch bound to 7-deazaguanine · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Elsewhere: RCSB PDB 4LVW · PDBe 4LVW

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