MolNFT v1 · #99149 · protein
Fragment-based discovery of a potent inhibitor of replication protein a protein-protein interactions
4LUZ · Replication protein a 70 kda DNA-binding subunit: “Fragment-based discovery of a potent inhibitor of replication protein a protein-protein interactions”. X-ray diffraction, 1 ligand (1XT). MolNFT v1 #99149 on GenesisL1: 3D…
- PDB
- 4LUZ
- Type
- protein
- Length
- 123 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Replication protein a 70 kda DNA-binding subunit
- UniProt
- P27694
- Ligands
- 1XT
Structure
x-ray diffraction · 1 distinct chain · 20% helix, 41% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Replication protein a 70 kda DNA-binding subunit | protein | 123 | 20% helix, 41% strand | P27694 |
Ligands and binding sites
- 1XT · 5-(4-{[4-(5-carboxyfuran-2-yl)benzyl]oxy}phenyl)-1-(3-methylphenyl)-1H-pyrazole-3-carboxylic acid · ligand · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Compared structures
- 4LUZ · Fragment-Based Discovery of a Potent Inhibitor of Replication Protein A Protein-Protein… · the same entry in another collection · chain A against A, TM-score 1.00
- P27694 · AlphaFold monomer V2.0 prediction for replication protein a 70 kda DNA-binding subunit… · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P27694
- Elsewhere: RCSB PDB 4LUZ · PDBe 4LUZ · UniProt P27694
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