MolNFT v1 · #99107 · protein
Bacterial sodium channel in high calcium, I222 space group, crystal 2
4LTP · Ion transport protein: “Bacterial sodium channel in high calcium, I222 space group, crystal 2”. X-ray diffraction, 1 ligand (CA), 5 pockets (best druggability 0.79). MolNFT v1 #99107 on GenesisL1: 3D structure, binding sites and…
- PDB
- 4LTP
- Type
- protein
- Length
- 552 residues
- Chains
- 4
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ion transport protein
- UniProt
- Q0ABW0
- Ligands
- CA
- Pockets
- 5 · best druggability 0.79
Structure
x-ray diffraction · 1 distinct chain · 79% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C, D | Ion transport protein | protein | 138 | 79% helix, 0% strand | Q0ABW0 |
Ligands and binding sites
- CA · Calcium ion · metal · 7 copies · chains A, B, C, D
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
5 pockets found on a 1 Å grid, 3 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 1128 | 0.79 | 0.80 | 75 | empty |
| 2 | 1157 | 0.75 | 0.77 | 66 | CA |
| 3 | 105 | 0.58 | 0.85 | 22 | empty |
| 4 | 50 | 0.28 | 0.75 | 11 | empty |
| 5 | 51 | 0.26 | 0.73 | 12 | empty |
Interfaces
6 interfaces between chains.
- B–C · 1452 Ų buried · 11 hydrogen bonds · protein-protein
- A–B · 1443 Ų buried · 11 hydrogen bonds · protein-protein
- C–D · 1348 Ų buried · 11 hydrogen bonds · protein-protein
- A–D · 1328 Ų buried · 10 hydrogen bonds · protein-protein
- A–C · 75 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 4LTP · Bacterial sodium channel in high calcium, I222 space group, crystal 2 · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q0ABW0
- Elsewhere: RCSB PDB 4LTP · PDBe 4LTP · UniProt Q0ABW0
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.