MolNFT v1 · #98993 · protein

Crystal structure of uncharacterized protein KFLA3161

4LQB: “Crystal structure of uncharacterized protein KFLA3161”. X-ray diffraction, 3 pockets (best druggability 0.44). MolNFT v1 #98993 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4LQB
Type: protein
Length: 258 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Uncharacterized protein
UniProt: D2Q399
Pockets: 3 · best druggability 0.44

Structure

x-ray diffraction · 2 distinct chains · 25% helix, 40% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Uncharacterized protein	protein	130	25% helix, 39% strand	D2Q399
B	Uncharacterized protein	protein	128	25% helix, 40% strand	D2Q399

Ligands and binding sites

GOL · Glycerol · additive · 3 copies · chains A, B
CIT · Citric acid · additive · chains B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	63	0.44	0.82	18	empty
2	102	0.41	0.76	12	GOL
3	89	0.39	0.76	16	GOL

Interfaces

1 interface between chains.

A–B · 1531 Å² buried · 10 hydrogen bonds · protein-protein

Modifications

Observed in the structure: 2 modified (engineered).

Compared structures

4LQB · Crystal structure of uncharacterized protein Kfla3161 · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt D2Q399
Elsewhere: RCSB PDB 4LQB · PDBe 4LQB · UniProt D2Q399

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