MolNFT v1 · #98991 · protein
Rickettsia rickettsii cell surface antigen 4 (SCA4) head domain (residues 21-360)
4LQ8 · Sca-family protein: “Rickettsia rickettsii cell surface antigen 4 (SCA4) head domain (residues 21-360)”. X-ray diffraction, 9 pockets (best druggability 0.56). MolNFT v1 #98991 on GenesisL1: 3D structure, binding sites and pockets…
- PDB
- 4LQ8
- Type
- protein
- Length
- 598 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sca-family protein
- UniProt
- E3T8S6
- Pockets
- 9 · best druggability 0.56
Structure
x-ray diffraction · 2 distinct chains · 33% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Sca-family protein | protein | 297 | 32% helix, 31% strand | E3T8S6 |
| B | Sca-family protein | protein | 301 | 34% helix, 30% strand | E3T8S6 |
Pockets
9 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 206 | 0.56 | 0.79 | 42 | empty |
| 2 | 129 | 0.49 | 0.79 | 22 | empty |
| 3 | 137 | 0.48 | 0.78 | 19 | empty |
| 4 | 116 | 0.46 | 0.78 | 22 | empty |
| 5 | 132 | 0.45 | 0.77 | 23 | empty |
Interfaces
1 interface between chains.
- A–B · 625 Ų buried · 7 hydrogen bonds · protein-protein
Compared structures
- 4LQ8 · Rickettsia rickettsii cell surface antigen 4 (sca4) head domain (residues 21-360) · the same entry in another collection · chain B against B, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt E3T8S6
- Elsewhere: RCSB PDB 4LQ8 · PDBe 4LQ8 · UniProt E3T8S6
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