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Rickettsia rickettsii cell surface antigen 4 (SCA4) head domain (residues 21-360)

Analyse Rickettsia rickettsii cell surface antigen 4 (SCA4) head domain (residues… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB: 4LQ8
Type: protein
Length: 598 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sca-family protein
UniProt: E3T8S6
Pockets: 9 · best druggability 0.56

Structure

x-ray diffraction · 2 distinct chains · 33% helix, 30% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sca-family protein	protein	297	32% helix, 31% strand	E3T8S6
B	Sca-family protein	protein	301	34% helix, 30% strand	E3T8S6

Pockets

9 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	206	0.56	0.79	42	empty
2	129	0.49	0.79	22	empty
3	137	0.48	0.78	19	empty
4	116	0.46	0.78	22	empty
5	132	0.45	0.77	23	empty

Interfaces

1 interface between chains.

A–B · 625 Å² buried · 7 hydrogen bonds · protein-protein

Compared structures

4LQ8 · Rickettsia rickettsii cell surface antigen 4 (sca4) head domain (residues 21-360) · the same entry in another collection · chain B against B, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt E3T8S6
Elsewhere: RCSB PDB 4LQ8 · PDBe 4LQ8 · UniProt E3T8S6

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