MolNFT v1 · #9899 · protein

Importin alpha, mouse

1IAL: “Importin alpha, mouse”. X-ray diffraction, 2 pockets (best druggability 0.48). MolNFT v1 #9899 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1IAL
Type: protein
Length: 438 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Importin alpha
UniProt: P52293
Pockets: 2 · best druggability 0.48

Structure

x-ray diffraction · 1 distinct chain · 72% helix, 0% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Importin alpha	protein	438	72% helix, 0% strand	P52293

Pockets

2 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	71	0.48	0.83	12	empty
2	74	0.31	0.74	13	empty

Compared structures

1IAL · Importin alpha, mouse · the same entry in another collection · chain A against A, TM-score 1.00
P52293 · AlphaFold monomer V2.0 prediction for importin subunit alpha-1 (P52293) · a predicted model of the same protein · chain A against A, TM-score 0.99

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P52293
Elsewhere: RCSB PDB 1IAL · PDBe 1IAL · UniProt P52293

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