MolNFT v1 · #98910 · protein

The first SH3 domain from CAP/PONSIN in complex with proline rich peptide from vinculin

4LNP · Sorbin and SH3 domain-containing protein 1: “The first SH3 domain from CAP/PONSIN in complex with proline rich peptide from vinculin”. X-ray diffraction. MolNFT v1 #98910 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4LNP
Type: protein
Length: 71 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sorbin and SH3 domain-containing protein 1; Vinculin
UniProt: Q9BX66, P18206

Structure

x-ray diffraction · 2 distinct chains · 4% helix, 42% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sorbin and SH3 domain-containing protein 1	protein	61	5% helix, 49% strand	Q9BX66
B	Vinculin	protein	10	0% helix, 0% strand	P18206

Interfaces

1 interface between chains.

A–B · 486 Å² buried · 5 hydrogen bonds · protein-protein

Compared structures

4LNP · The first SH3 domain from CAP/Ponsin in complex with proline rich peptide from Vinculin · the same entry in another collection · chain A against A, TM-score 1.00
Q9BX66 · AlphaFold monomer V2.0 prediction for sorbin and SH3 domain- containing protein 1 (Q9BX66) · a predicted model of the same protein · chain A against A, TM-score 0.93
P18206 · AlphaFold monomer V2.0 prediction for vinculin (P18206) · a predicted model of the same protein · chain B against A, TM-score 0.41

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt Q9BX66
Every structure of UniProt P18206
Elsewhere: RCSB PDB 4LNP · PDBe 4LNP · UniProt Q9BX66 · UniProt P18206

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