MolNFT v1 · #9861 · protein
Core streptavidin-bna complex
1I9H: “Core streptavidin-bna complex”. X-ray diffraction, 1 ligand (BNI), 3 pockets (best druggability 0.47). MolNFT v1 #9861 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 1I9H
- Type
- protein
- Length
- 244 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Streptavidin
- UniProt
- P22629
- Ligands
- BNI
- Pockets
- 3 · best druggability 0.47
Structure
x-ray diffraction · 2 distinct chains · 5% helix, 55% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Streptavidin | protein | 121 | 5% helix, 56% strand | P22629 |
| B | Streptavidin | protein | 123 | 5% helix, 54% strand | P22629 |
Ligands and binding sites
- BNI · 5-(2-oxo-hexahydro-thieno[3,4-d]imidazol-6-yl)-pentanoic acid (4-nitro-phenyl)-amide · ligand · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
3 pockets found on a 1 Å grid, 0 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 95 | 0.47 | 0.80 | 18 | BNI |
| 2 | 90 | 0.46 | 0.80 | 18 | BNI |
| 3 | 60 | 0.30 | 0.76 | 21 | empty |
Interfaces
1 interface between chains.
- A–B · 1616 Ų buried · 26 hydrogen bonds · protein-protein
Compared structures
- 1I9H · Core streptavidin-bna complex · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P22629
- Elsewhere: RCSB PDB 1I9H · PDBe 1I9H · UniProt P22629
GL1X is a live explorer of the GenesisL1 blockchain. Turn on JavaScript for search, charts and interactive views.