MolNFT v1 · #98382 · protein
Crystal structure of protein L-isoaspartyl-O-methyltransferase of vibrio cholerae
4L7V · Protein-L-isoaspartate O-methyltransferase: “Crystal structure of protein L-isoaspartyl-O-methyltransferase of vibrio cholerae”. X-ray diffraction, 2 ligands (SAH, CA), 1 pocket (best druggability 0.57). MolNFT v1 #98382 on…
- PDB
- 4L7V
- Type
- protein
- Length
- 186 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Protein-L-isoaspartate O-methyltransferase
- EC
- 2.1.1.77
- UniProt
- A5F9C1
- Ligands
- SAH, CA
- Pockets
- 1 · best druggability 0.57
Structure
x-ray diffraction · 1 distinct chain · 33% helix, 30% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Protein-L-isoaspartate O-methyltransferase (EC 2.1.1.77) | protein | 186 | 33% helix, 30% strand | A5F9C1 |
Ligands and binding sites
- SAH · S-adenosyl-L-homocysteine · ligand · chains A
- CA · Calcium ion · metal · chains A
- ACT · Acetate ion · additive · chains A
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 309 | 0.57 | 0.76 | 36 | SAH |
Compared structures
- 4L7V · Crystal structure of Protein L-isoaspartyl-O-methyltransferase of Vibrio cholerae · the same entry in another collection · chain A against A, TM-score 1.00
- A5F9C1 · AlphaFold monomer V2.0 prediction for protein-L-isoaspartate O-methyltransferase (A5F9C1) · a predicted model of the same protein · chain A against A, TM-score 0.98
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt A5F9C1
- Elsewhere: RCSB PDB 4L7V · PDBe 4L7V · UniProt A5F9C1
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