MolNFT v1 · #97479 · protein

NUP188(AA1-1160) from myceliophthora thermophila

4KF7: “NUP188(AA1-1160) from myceliophthora thermophila”. X-ray diffraction, 16 pockets (best druggability 0.81). MolNFT v1 #97479 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4KF7
Type: protein
Length: 1,096 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: NUP188
UniProt: G2QD05
Pockets: 16 · best druggability 0.81

Structure

x-ray diffraction · 1 distinct chain · 64% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	NUP188	protein	1096	64% helix, 3% strand	G2QD05

Pockets

16 pockets found on a 1 Å grid, 4 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	1182	0.81	0.82	99	empty
2	978	0.78	0.80	84	empty
3	218	0.61	0.81	39	empty
4	255	0.59	0.79	32	empty
5	151	0.50	0.78	24	empty

Compared structures

4KF7 · Nup188(aa1-1160) from Myceliophthora thermophila · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt G2QD05
Elsewhere: RCSB PDB 4KF7 · PDBe 4KF7 · UniProt G2QD05

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