MolNFT v1 · #96231 · protein
Structure of the fluorescence recovery protein from synechocystis sp pcc 6803, R60K mutant
4JDQ · SLR1964 protein: “Structure of the fluorescence recovery protein from synechocystis sp pcc 6803, R60K mutant”. X-ray diffraction, 5 pockets (best druggability 0.67). MolNFT v1 #96231 on GenesisL1: 3D structure, binding sites and…
- PDB
- 4JDQ
- Type
- protein
- Length
- 583 residues
- Chains
- 6
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- SLR1964 protein
- UniProt
- P74103
- Pockets
- 5 · best druggability 0.67
Structure
x-ray diffraction · 4 distinct chains · 76% helix, 0% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B, C | SLR1964 protein | protein | 102 | 74% helix, 0% strand | P74103 |
| D | SLR1964 protein | protein | 97 | 73% helix, 0% strand | P74103 |
| E | SLR1964 protein | protein | 90 | 80% helix, 0% strand | P74103 |
| F | SLR1964 protein | protein | 90 | 77% helix, 0% strand | P74103 |
Pockets
5 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 391 | 0.67 | 0.80 | 40 | empty |
| 2 | 157 | 0.47 | 0.76 | 24 | empty |
| 3 | 124 | 0.46 | 0.78 | 21 | empty |
| 4 | 85 | 0.35 | 0.75 | 16 | empty |
| 5 | 70 | 0.33 | 0.75 | 12 | empty |
Interfaces
6 interfaces between chains.
- E–F · 1857 Ų buried · 23 hydrogen bonds · protein-protein
- B–D · 969 Ų buried · 3 hydrogen bonds · protein-protein
- A–D · 791 Ų buried · 8 hydrogen bonds · protein-protein
- A–C · 622 Ų buried · 11 hydrogen bonds · protein-protein
- B–E · 132 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 4JDQ · Structure of the Fluorescence Recovery Protein from Synechocystis sp PCC 6803, R60K mutant · the same entry in another collection · chain F against F, TM-score 1.00
- P74103 · AlphaFold monomer V2.0 prediction for fluorescence recovery protein (P74103) · a predicted model of the same protein · chain C against A, TM-score 0.97
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P74103
- Elsewhere: RCSB PDB 4JDQ · PDBe 4JDQ · UniProt P74103
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