MolNFT v1 · #96073 · protein

Crystal structure of FGF receptor 2 (FGFR2) kinase domain harboring the pathogenic gain-of-function K659E mutation identified in endometrial cancer.

4J97: “Crystal structure of FGF receptor 2 (FGFR2) kinase domain harboring the pathogenic gain-of-function K659E…”. X-ray diffraction. MolNFT v1 #96073 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 4J97
Type: protein
Length: 1,133 residues
Chains: 4
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
UniProt: P21802

Structure

x-ray diffraction · 4 distinct chains.

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	—	protein	282	—	P21802
B	—	protein	283	—	P21802
C	—	protein	283	—	P21802
D	—	protein	285	—	P21802

Compared structures

4J97 · Crystal Structure of FGF Receptor 2 (FGFR2) Kinase Domain Harboring the Pathogenic… · the same entry in another collection · chain D against D, TM-score 1.00
P21802 · AlphaFold monomer V2.0 prediction for fibroblast growth factor receptor 2 (P21802) · a predicted model of the same protein · chain A against A, TM-score 0.98

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P21802
Elsewhere: RCSB PDB 4J97 · PDBe 4J97 · UniProt P21802

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