MolNFT v1 · #95641 · protein
Crystal structure of 8-amino-7-oxononanoate synthase (biof) from francisella tularensis.
4IW7: “Crystal structure of 8-amino-7-oxononanoate synthase (biof) from francisella tularensis.”. X-ray diffraction, 2 pockets (best druggability 0.51). MolNFT v1 #95641 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4IW7
- Type
- protein
- Length
- 335 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- 8-amino-7-oxononanoate synthase
- EC
- 2.3.1.47
- UniProt
- Q5NGB3
- Pockets
- 2 · best druggability 0.51
Structure
x-ray diffraction · 1 distinct chain · 45% helix, 17% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | 8-amino-7-oxononanoate synthase (EC 2.3.1.47) | protein | 335 | 45% helix, 17% strand | Q5NGB3 |
Pockets
2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 169 | 0.51 | 0.78 | 36 | empty |
| 2 | 93 | 0.48 | 0.81 | 20 | empty |
Modifications
Observed in the structure: 1 modified (oxidation).
Compared structures
- 4IW7 · Crystal structure of 8-amino-7-oxononanoate synthase (bioF) from Francisella tularensis. · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt Q5NGB3
- Elsewhere: RCSB PDB 4IW7 · PDBe 4IW7 · UniProt Q5NGB3
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