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Crystal structure of 8-amino-7-oxononanoate synthase (biof) from francisella tularensis.

Analyse Crystal structure of 8-amino-7-oxononanoate synthase (biof) from francisella… in the GL1X research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides, crosslinks and neighbours on the 3D structure.

PDB
4IW7
Type
protein
Length
335 residues
Chains
1
Method
x-ray diffraction
Collection
MolNFT v1 / PDB
Contract
0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner
0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule
8-amino-7-oxononanoate synthase
EC
2.3.1.47
UniProt
Q5NGB3
Pockets
2 · best druggability 0.51

Structure

x-ray diffraction · 1 distinct chain · 45% helix, 17% strand (DSSP).

ChainMoleculeTypeResiduesSecondary structureUniProt
A8-amino-7-oxononanoate synthase (EC 2.3.1.47)protein33545% helix, 17% strandQ5NGB3

Pockets

2 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.

PocketVolume (ų)DruggabilityBuriednessLining residuesInside
11690.510.7836empty
2930.480.8120empty

Modifications

Observed in the structure: 1 modified (oxidation).

Compared structures

  • 4IW7 · Crystal structure of 8-amino-7-oxononanoate synthase (bioF) from Francisella tularensis. · the same entry in another collection · chain A against A, TM-score 1.00

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