MolNFT v1 · #94767 · protein
Crystal structure of rabbit ryanodine receptor 1 (residues 1-559) disease mutant R45C
4I6I: “Crystal structure of rabbit ryanodine receptor 1 (residues 1-559) disease mutant R45C”. X-ray diffraction, 3 pockets (best druggability 0.70). MolNFT v1 #94767 on GenesisL1: 3D structure, binding sites and pockets in GL1X.
- PDB
- 4I6I
- Type
- protein
- Length
- 451 residues
- Chains
- 1
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Ryanodine receptor 1
- UniProt
- P11716
- Pockets
- 3 · best druggability 0.70
Structure
x-ray diffraction · 1 distinct chain · 25% helix, 32% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A | Ryanodine receptor 1 | protein | 451 | 25% helix, 32% strand | P11716 |
Pockets
3 pockets found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 413 | 0.70 | 0.82 | 37 | empty |
| 2 | 217 | 0.46 | 0.74 | 31 | empty |
| 3 | 113 | 0.45 | 0.78 | 25 | empty |
Compared structures
- 4I6I · Crystal structure of rabbit ryanodine receptor 1 (residues 1-559) disease mutant R45C · the same entry in another collection · chain A against A, TM-score 1.00
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P11716
- Elsewhere: RCSB PDB 4I6I · PDBe 4I6I · UniProt P11716
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