MolNFT v1 · #94337 · protein
Crystal structure of twin arginine translocase receptor- tatc in ddm
4HTT · Sec-independent protein translocase protein tatc, lysozyme: “Crystal structure of twin arginine translocase receptor- tatc in ddm”. X-ray diffraction, 9 pockets (best druggability 0.54). MolNFT v1 #94337 on GenesisL1: 3D structure…
- PDB
- 4HTT
- Type
- protein
- Length
- 450 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Sec-independent protein translocase protein tatc, lysozyme
- EC
- 3.2.1.17
- UniProt
- O67305, P00720
- Pockets
- 9 · best druggability 0.54
Structure
x-ray diffraction · 1 distinct chain · 71% helix, 1% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Sec-independent protein translocase protein tatc, lysozyme (EC 3.2.1.17) | protein | 225 | 71% helix, 1% strand | O67305, P00720 |
Pockets
9 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 175 | 0.54 | 0.79 | 28 | empty |
| 2 | 161 | 0.51 | 0.78 | 24 | empty |
| 3 | 69 | 0.44 | 0.81 | 19 | empty |
| 4 | 109 | 0.42 | 0.76 | 16 | empty |
| 5 | 59 | 0.41 | 0.80 | 17 | empty |
Interfaces
1 interface between chains.
- A–B · 397 Ų buried · 0 hydrogen bonds · protein-protein
Compared structures
- 4HTT · Crystal Structure of Twin Arginine Translocase Receptor- TatC in DDM · the same entry in another collection · chain A against A, TM-score 1.00
- O67305 · AlphaFold monomer V2.0 prediction for sec-independent protein translocase protein tatc… · a predicted model of the same protein · chain A against A, TM-score 0.95
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt O67305
- Every structure of UniProt P00720
- Elsewhere: RCSB PDB 4HTT · PDBe 4HTT · UniProt O67305 · UniProt P00720
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