MolNFT v1 · #94187 · protein

The crystal structure of isomaltulose synthase mutant D241A from erwinia rhapontici NX5 in complex with D-glucose

4HOZ · Sucrose isomerase: “The crystal structure of isomaltulose synthase mutant D241A from erwinia rhapontici NX5 in complex with…”. X-ray diffraction, 2 ligands (GLC, CA), 6 pockets (best druggability 0.76). MolNFT v1 #94187 on…

PDB: 4HOZ
Type: protein
Length: 559 residues
Chains: 1
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Sucrose isomerase
EC: 5.4.99.11
UniProt: D9MPF2
Ligands: GLC, CA
Pockets: 6 · best druggability 0.76

Structure

x-ray diffraction · 1 distinct chain · 33% helix, 18% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A	Sucrose isomerase (EC 5.4.99.11)	protein	559	33% helix, 18% strand	D9MPF2

Ligands and binding sites

GLC · alpha-D-glucopyranose · sugar · chains A
CA · Calcium ion · metal · chains A
GOL · Glycerol · additive · chains A

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

6 pockets found on a 1 Å grid, 2 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	102	0.76	0.97	22	GOL, GLC
2	199	0.60	0.82	22	empty
3	86	0.40	0.78	20	empty
4	142	0.40	0.73	28	empty
5	78	0.36	0.76	17	empty

Compared structures

4HOZ · The crystal structure of isomaltulose synthase mutant D241A from Erwinia rhapontici NX5… · the same entry in another collection · chain A against A, TM-score 1.00

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt D9MPF2
Elsewhere: RCSB PDB 4HOZ · PDBe 4HOZ · UniProt D9MPF2

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