MolNFT v1 · #9383 · protein
Human ADP-ribosylation factor 1 complexed with GDP, full length non-myristoylated
1HUR: “Human ADP-ribosylation factor 1 complexed with GDP, full length non-myristoylated”. X-ray diffraction, 2 ligands (GDP, MG), 1 pocket (best druggability 0.67). MolNFT v1 #9383 on GenesisL1: 3D structure, binding sites and pockets in…
- PDB
- 1HUR
- Type
- protein
- Length
- 360 residues
- Chains
- 2
- Method
- x-ray diffraction
- Collection
- MolNFT v1 / PDB
- Contract
- 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
- Owner
- 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
- Molecule
- Human ADP-ribosylation factor 1
- UniProt
- P84077
- Ligands
- GDP, MG
- Pockets
- 1 · best druggability 0.67
Structure
x-ray diffraction · 1 distinct chain · 31% helix, 26% strand (DSSP).
| Chain | Molecule | Type | Residues | Secondary structure | UniProt |
|---|---|---|---|---|---|
| A, B | Human ADP-ribosylation factor 1 | protein | 180 | 31% helix, 26% strand | P84077 |
Ligands and binding sites
- GDP · Guanosine-5'-diphosphate · ligand · 2 copies · chains A, B
- MG · Magnesium ion · metal · 2 copies · chains A, B
Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.
Pockets
1 pocket found on a 1 Å grid, 1 with a druggability of 0.5 or more.
| Volume (ų) | Druggability | Buriedness | Lining residues | Inside | |
|---|---|---|---|---|---|
| 1 | 635 | 0.67 | 0.76 | 70 | MG, GDP |
Interfaces
1 interface between chains.
- A–B · 574 Ų buried · 4 hydrogen bonds · protein-protein
Compared structures
- 1HUR · Human ADP-ribosylation factor 1 complexed with GDP, full length non-myristoylated · the same entry in another collection · chain A against A, TM-score 1.00
- P84077 · AlphaFold monomer V2.0 prediction for ADP-ribosylation factor 1 (P84077) · a predicted model of the same protein · chain A against A, TM-score 0.80
Analyse
- Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
- Every structure of UniProt P84077
- Elsewhere: RCSB PDB 1HUR · PDBe 1HUR · UniProt P84077
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