MolNFT v1 · #9339 · protein

Domain swapping ef-hands

1HT9 · Calbindin D9K: “Domain swapping ef-hands”. X-ray diffraction, 1 ligand (CA), 1 pocket (best druggability 0.25). MolNFT v1 #9339 on GenesisL1: 3D structure, binding sites and pockets in GL1X.

PDB: 1HT9
Type: protein
Length: 152 residues
Chains: 2
Method: x-ray diffraction
Collection: MolNFT v1 / PDB
Contract: 0xDE3723766Bc32dcACD03C17BaA400A7B36837Eba
Owner: 0x3396CDB397284571d12822B4ae1189a8E22AAAAA
Molecule: Calbindin D9K
UniProt: P02633
Ligands: CA
Pockets: 1 · best druggability 0.25

Structure

x-ray diffraction · 1 distinct chain · 64% helix, 3% strand (DSSP).

Chain	Molecule	Type	Residues	Secondary structure	UniProt
A, B	Calbindin D9K	protein	76	64% helix, 3% strand	P02633

Ligands and binding sites

CA · Calcium ion · metal · 4 copies · chains A, B

Binding sites are the residues within 4.5 Å of a ligand's heavy atoms.

Pockets

1 pocket found on a 1 Å grid, 0 with a druggability of 0.5 or more.

Pocket	Volume (Å³)	Druggability	Buriedness	Lining residues	Inside
1	52	0.25	0.73	12	empty

Interfaces

1 interface between chains.

A–B · 2008 Å² buried · 16 hydrogen bonds · protein-protein

Compared structures

1HT9 · Domain swapping ef-hands · the same entry in another collection · chain A against A, TM-score 1.00
P02633 · AlphaFold monomer V2.0 prediction for protein S100-G (P02633) · a predicted model of the same protein · chain A against A, TM-score 0.56

Analyse

Open in the research workbench: secondary structure, accessibility, pockets, interfaces, conservation, variants, modifications, peptides and crosslinks on the 3D structure
Every structure of UniProt P02633
Elsewhere: RCSB PDB 1HT9 · PDBe 1HT9 · UniProt P02633

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